icobrain dm

objectively quantify relevant brain structures in individual dementia patients

How to interpret your icobrain dm report

info qc visualResults brainVolumes flair softwareVersion
  • INFO

    MRI dates = dates of the MRI scans on which the report is based. When only one MRI exam is available, a baseline report is created which reports volumes but no volume changes.

  • QC

    Status of semi automated quality control (Approved / Approved with remarks / rejected) and remarks on the quality of the original images and the segmentation.


    Color-coded segmentation of substructures

    • Frontal cortex (green)
    • Parietal cortex (blue)
    • Temporal cortex (red)
    • Hippocampi (orange)

    This segmentation is also available in DICOM format.


    Brain volumes are corrected for head size. The normal range and normative percentiles serve as a reference based on healthy controls. Annualized volume change describes the percentage of brain volume change per year compared to the previous scan. The normal annualized volume change represents the average expected annual volume change for a healthy age- and gender-matched person.

    Population graphs show the age- and gender-matched average and normal ranges for each substructure.The current (black) and previous (white) time points are marked with an ‘x’. The error bars are computed from the pooled results of several test-retest experiments.They represent the interval in which the differences between test- and retest results can be found with 90% confidence.

    Volume signature compares the normative percentile of the substructures and its change between the current (full black line) and previous (dashed white line) time point.


    Flair white matter hyperintensities are reported when a FLAIR sequence is included.
    Volume change = total difference in volume compared to the previous scan.


    The icobrain software version and its approval for clinical practice.

Segmentation interpretation

Hover over the segmentations

Frontal cortex
Parietal cortex
Temporal cortex
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