objectively track disease progression in individual multiple sclerosis patients
MRI dates = dates of the MRI scans on which the report is based. When only one MRI exam is available, a baseline report is created which reports volumes but no volume changes.
Status (Approved / Approved with remarks / Rejected / Unusable) and remarks on the quality of the original images and the reported values.
Color-coded segmentation of FLAIR white matter (WM) hyperintensities
This segmentation is also available in DICOM format.
FLAIR WM hyperintensities and T1 WM hypointensities are always repor
ted.
For post-C T1 sequences, the T1 WM hyperintensities are also reported
Volume change = total difference in volume compared to the previous scan
New + Enlarging – Shrinking (includes disappearing) = Volume change
The bar chart shows the volume and error bars at time point 1 (t1), time point 2 (t2) and the change () for
each location (periventricular, juxtacortical, infratentorial, and deep white matter). The error bars are
computed from the pooled results of several test-retest experiments. They represent the interval in which the
differences between test- and retest results can be found with 90% confidence.
Total, new, enlarging and shrinking volumes are indicated for each location.
New + Enlarging - Shrinking = △
Percentage of total volume (%) is indicated for each location.
The icobrain software version and its approval for clinical practice.
MRI dates = dates of the MRI scans on which the report is based. When only one MRI exam is available, a baseline report is created which reports volumes but no volume changes.
T1 white matter (WM) hypointensities (red) and gray matter (blue) segmentation.
This segmentation is also available in DICOM format.
Whole brain and gray matter volumes are corrected for head size.
The normal range and normative percentiles serve as a reference based on
healthy controls.
Annualized volume change describes the percentage of brain volume change per year compared to
the previous scan.
The normal annualized volume change represents the average expected annual volume change for a healthy age-
and gender-matched person.
The graph shows the age- and gender-matched average and normal range for the whole brain (left) and gray
matter (right) volume of healthy people.The current (black) and previous (white) time points are marked with
an 'x'.
The error bars are computed from the pooled results of several test-retest experiments.They represent the
interval in which the differences between test- and retest results can be found with 90% confidence.
The icobrain software version and its approval for clinical practice.
Hover over the segmentations
NEW
ENLARGING
STABLE